Prenatal exposures to help you organophosphate ester metabolite blends and students’s neurobehavioral consequences in the MADRES pregnancy cohort

Prenatal exposures to help you organophosphate ester metabolite blends and students’s neurobehavioral consequences in the MADRES pregnancy cohort

Evidence ways organophosphate esters (OPEs) is neurotoxic; but not, the fresh epidemiological books stays scarce. We investigated if or not prenatal exposures so you’re able to OPEs was indeed of the child neurobehavior regarding the MADRES cohort.

Methods

We measured nine OPE metabolites in 204 maternal urine samples (gestational age at collection: 31.4 ± 1.8 weeks). Neurobehavior problems were assessed among 36-month-old children using the Child Behavior Checklist’s (CBCL) three composite scales [internalizing, externalizing, and total problems]. We examined associations between tertiles of prenatal OPE metabolites (> 50% detection) and detect/non-detect categories (< 50%>